对小鼠研究提示,运动可以促进阿尔茨海默氏症患者的脑细胞生长《合众国际社》 - Exercise can boost brain cell growth in Alzheimer's, mouse study suggests-华东公共卫生
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对小鼠研究提示,运动可以促进阿尔茨海默氏症患者的脑细胞生长《合众国际社》

Exercise can boost brain cell growth in Alzheimer's, mouse study suggests

[日期:2018-09-08] 来源:UPI  作者:华东公共卫生 录入 [字体: ]

为了健康

运动与老年痴呆

Researchers report that physical activity promoted the growth of brain cells that improved thinking in mice with a form of Alzheimer's disease. Photo by pasja1000/Pixabay

      《合众国际社 UPI》"While we do not yet have the means for safely achieving the same effects in patients, we determined the precise protein and gene targets for developing ways to do so in the future," study lead author Se Hoon Choi said in an MGH news release. Choi is in the hospital's genetics and aging research unit.
      In mice, Choi's team said exercise triggered the production of new neurons (neurogenesis) in the brain regions where memories are encoded.
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      The study's senior author, Rudolph Tanzi, is director of the genetics and aging research unit at MGH. He said that the research team "showed that exercise is one of the best ways to turn on neurogenesis. And then, by figuring out the molecular and genetic events involved, we determined how to mimic the beneficial effects of exercise through gene therapy and pharmacological agents."
      Results of animal studies aren't always replicated in people, but Tanzi is optimistic.
      "We will next explore whether safely promoting neurogenesis in Alzheimer's patients will help alleviate the symptoms of the disease, and whether doing so in currently healthy individuals earlier in life can help prevent symptoms later on," Tanzi said.
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      The study was published Sept. 6 in the journal Science.
More information
      The U.S. National Institute on Aging has more about Alzheimer's disease.

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